Week 2 Updates: Module 2 What Makes a Good Screen?

Module 2: What makes a good screen was designed to define key terms and differentiate target-based and phenotypic screens to evaluate when each is appropriate. We will discuss Z-factors and how they are used to determine the quality of a given assay. 

This week you will also meet your Lab Project Team members when we meet TODAY at 12:50 pm on Tuesday, January 18 using our course Zoom link. While this is an asynchronous course, we do expect you to reserve your scheduled lab time to alleviate schedule conflicts that can make collaborative work more challenging than need be. 

Upon successful completion of this module, you will be able to:

  1. MO 2.1. Define the following terms: miniaturization and reproducibility. (CO 1)
  2. MO 2.2. Compare and contrast target-based vs. phenotypic screens, and determine situations in which each is appropriate. (CO 4)
  3. MO 2.3. Define and calculate Z-factor, and use it to determine the quality of a given assay. (CO 2)

Your HTD Instructional Team

Dr. Carlos Goller | email: ccgoller@ncsu.edu 

Dr. Carly Sjogren | email: casjogre@ncsu.edu