Module 4

Next week our fourth quest begins: Module 4:  What compounds are available? This is one of my favorite ones!

What compounds are available out there for chemical screens?

What is the chemical space?

To answer these questions, we will introduce key terms and approaches to discover, create, and test novel compounds in a variety of different assays.

We will analyze how false positives and false-negative rates are calculated and how IC50 values are determined.

We will look at the MLPCN results and current and future related projects with the goal of identifying useful probes and effective therapeutics!

There are Top Hat questions associated with this Module and a case study and forum. I look forward to another round of online conversations!

We have posted our fourth Mix Tape and attached it here. A short video is available on Moodle, and the slides are available both on our Moodle site and on Top Hat. Again, you will have a series of questions to respond to on Top Hat and a discussion forum based on our second case study. Please pay close attention to our Module Objectives and keep them in mind for our discussion forum.

Let’s begin our fourth quest!

CG

BIT 479/579 High-throughput Discovery Mix Tape 4
Cassette tape and link to audio recording for session.

Mix Tape 4 mp3

Mix Tape 4 transcript

Music: Don’t Feel (So Low) and Four Corners {103 & 4/4} by Mid-Air Machine are licensed under an Attribution-ShareAlike License and used as intros and outros for the videos and podcast.